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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC5
All Species:
4.24
Human Site:
S1081
Identified Species:
10.37
UniProt:
O75140
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75140
NP_001007189.1
1572
177910
S1081
M
D
S
P
R
K
V
S
V
D
Q
T
A
T
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852875
773
87442
T300
F
P
Q
G
D
N
S
T
S
A
Q
G
N
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
P61460
1527
173129
S1037
V
D
S
P
R
K
A
S
V
D
Q
T
A
P
L
Rat
Rattus norvegicus
NP_001100699
1456
164725
V982
L
D
S
T
S
L
G
V
S
T
C
Q
S
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517877
828
93963
Q355
L
L
M
I
L
T
K
Q
R
M
I
D
N
G
I
Chicken
Gallus gallus
XP_415249
1571
177723
V1080
Y
M
D
S
P
R
K
V
S
I
D
Q
S
V
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691450
1590
178752
C1099
S
P
R
S
S
Y
I
C
H
S
Q
L
P
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728620
1472
168864
R999
S
N
R
L
P
E
K
R
P
S
I
N
V
R
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794020
1608
181354
K1104
K
A
M
A
D
P
S
K
G
L
R
F
I
A
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S9J6
2004
222187
F1257
I
P
A
S
E
R
S
F
Q
A
S
R
R
K
K
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
48
N.A.
91.7
87.4
N.A.
49.5
89.1
N.A.
75.5
N.A.
35.7
N.A.
N.A.
32.4
Protein Similarity:
100
N.A.
N.A.
48.6
N.A.
93.8
89.6
N.A.
50.9
94
N.A.
84.5
N.A.
53.7
N.A.
N.A.
48.6
P-Site Identity:
100
N.A.
N.A.
6.6
N.A.
73.3
13.3
N.A.
0
6.6
N.A.
6.6
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
13.3
N.A.
80
26.6
N.A.
6.6
20
N.A.
13.3
N.A.
20
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
10
0
0
10
0
0
20
0
0
20
20
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% C
% Asp:
0
30
10
0
20
0
0
0
0
20
10
10
0
0
10
% D
% Glu:
0
0
0
0
10
10
0
0
0
0
0
0
0
0
10
% E
% Phe:
10
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
10
0
0
10
0
10
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
0
10
0
0
10
0
0
10
20
0
10
0
10
% I
% Lys:
10
0
0
0
0
20
30
10
0
0
0
0
0
10
10
% K
% Leu:
20
10
0
10
10
10
0
0
0
10
0
10
0
0
20
% L
% Met:
10
10
20
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
10
0
0
0
0
0
10
20
0
0
% N
% Pro:
0
30
0
20
20
10
0
0
10
0
0
0
10
10
40
% P
% Gln:
0
0
10
0
0
0
0
10
10
0
40
20
0
0
0
% Q
% Arg:
0
0
20
0
20
20
0
10
10
0
10
10
10
10
0
% R
% Ser:
20
0
30
30
20
0
30
20
30
20
10
0
20
0
0
% S
% Thr:
0
0
0
10
0
10
0
10
0
10
0
20
0
10
0
% T
% Val:
10
0
0
0
0
0
10
20
20
0
0
0
10
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _